PhD candidate, Virginia Tech

Education

B.E. Polymer Engineering, University of Pune, India.

M.S. Materials Science and Engineering, University of Cincinnati, Cincinnati, OH

Projects

To understand the structure-biological activity of the nucleic acid binding polymers, currently I am working towards the synthesis of monomers and polymers which involve subtle changes in their functionality in the repeat unit. These studies involve strategic design and organic synthesis of the monomers and polymers, its complexation with nucleic acids and physical characterization of these complexes and different biological assays to determine and compare its biological activity. Also, we have successfully built the layer-by-layer (LbL) assemblies containing alternate layers of Poly(L-tartaramidopentaethylenetetramine) (T4) and plasmid DNA (pDNA). We have monitored these LbL assemblies in the physiological environment and have successfully studied the controlled release of pDNA and its activity over 11 days from these LbL assemblies.

Publications

1. Taori V. P.; Liu Y.; Reineke T. M. "DNA delivery in-vitro via surface release from multilayer assemblies with Poly(glycoamidoamine)s" Acta Biomaterialia 2009, 5, 925 *Invited Paper: Part of the Self-Assembling Biomaterials Special Issue*

2. Patwardhan S. V.; Taori V. P.; Hassan M.; Agashe N. R.; Franklin J. E.; Beaucage G.; Mark J. E.; Clarson S. J. "An Investingation of the properrties of poly(dimethoxysiloxane)-bioinspired silica hybrids" European Polymer Journal 2006, 42, 167.

Contact

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